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Gene name:
AREG(SDGF);
Protein name:
Amphiregulin(AR);
Alternative:
Colorectum cell-derived growth factor(CRDGF);
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
The immature precursor interacts with CNIH.
Function:
Bifunctional growth-modulating glycoprotein. Inhibits growth of several human carcinoma cells in culture and stimulates proliferation of human fibroblasts and certain other tumor cells.
Subcellular Location:
Membrane Single-pass membrane protein
Protein Attributes:
Sequence length:
252
Sequence:
50:
MRAPLLPPAP | VVLSLLILGS | GHYAAGLDLN | DTYSGKREPF | SGDHSADGFE |
100:
VTSRSEMSSG | SEISPVSEMP | SSSEPSSGAD | YDYSEEYDNE | PQIPGYIVDD |
150:
SVRVEQVVKP | PQNKTESENT | SDKPKRKKKG | GKNGKNRRNR | KKKNPCNAEF |
200:
QNFCIHGECK | YIEHLEAVTC | KCQQEYFGER | CGEKSMKTHS | MIDSSLSKIA |
250:
LAAIAAFMSA | VILTAVAVIT | VQLRRQYVRK | YEGEAEERKK | LRQENGNVHA |
252:
IA
3D Structure:
2RNL | Help?
Predicted Eptitope:
N/A
Related Databases
UniGene:
Hs.270833
MIM:
104640
SMR:
P15514
STRING:
9606.ENSP00000264487
String:
P15514
KEGG:
hsa:374